IZUMI, Yoshihiro


e-mail address

yoshihiro_izumi@bio.eng.osaka-u.ac.jp

 

Specialism

Metabolomics (microorganism, plant, animal), Analytical chemistry, Mass spectrometry, DNA and RNA analyses with mass spectrometry 

 

Specialism

Metabolomics (microorganism, plant, animal), Analytical chemistry, Mass spectrometry, DNA and RNA analyses with mass spectrometry

 

Personal data

Birthday: April 2nd, 1980

Hometown: Kagawa

Blood type: A

Hobby: Football, Futsal, Music (Rock etc.), Watching movies, Mass spectrometry!!
 
(Publication List)

Original

1.       Kajiyama S, Shoji T, Okuda S, Izumi Y, Fukusaki E, Kobayashi A. A novel microsurgery method for intact plant tissue at the single cell level using ArF excimer laser microprojection. Biotechnol. Bioeng.93(2): 325-31 (2006).

2.       Nakamura R, Izumi Y, Kajiyama S, Kobayashi A, Kanematsu Y. Line-Scanning Microscopy for Time-Gated and Spectrally Resolved Fluorescence Imaging. J. Biol. Phys.34: 51-62 (2008).

3.       Igarashi D, Izumi Y, Dokiya Y, Totsuka K, Fukusaki E, Ohsumi C. Reproductive organs regulate leaf nitrogen metabolism mediated by cytokinin signal. Planta229(3): 633-644 (2009).

4.       Izumi Y, Kajiyama S, Nakamura R, Ishihara A, Okazawa A, Fukusaki E, Kanematsu Y, Kobayashi A. High-resolution spatial and temporal analysis of phytoalexin production in oats. Planta229(4): 931-943 (2009).

5.       Izumi Y, Okazawa A, Bamba T, Kobayashi A, Fukusaki E. Development of a method for comprehensive and quantitative analysis of plant hormones by highly sensitive nanoflow liquid chromatography-electrospray ionization-ion trap mass spectrometry. Anal. Chim. Acta648: 215-225 (2009).

6.       Okazawa A, Hori K, Okumura R, Izumi Y, Naoki H, Bamba T, Fukusaki, E, Ono E, Satake H, Kobayashi A. Simultaneous quantification of lignans in Arabidopsis thaliana by highly sensitive capillary liquid chromatography-electrospray ionization-ion trap mass spectrometry. Plant Biotechnol.28: 287-293 (2011).

7.       Sugimoto T, Bamba T, Izumi Y, Nomura H, Shiina T, Fukusaki E. Use of UPLC/TOF-MS with nozzle-skimmer fragmentation for comprehensive quantitative analysis of secondary metabolites in Arabidopsis thalianaJ. Sep. Sci.34: 3587-3596 (2011).

8.       Izumi Y, Takimura S, Yamaguchi S, Iida J, Bamba T, Fukusaki E. Application of electrospray ionization ion trap/time-of-flight mass spectrometry for chemically-synthesized small RNAs. J. Biosci. Bioeng.113(3): 412-419 (2012).

9.       Kato H, Izumi Y, Hasunuma T, Matsuda F, Kondo A. Widely targeted metabolic profiling analysis of yeast central metabolites. J. Biosci. Bioeng.113(5): 665-73 (2012).

10.   Aikawa S, Izumi Y, Matsuda F, Hasunuma T, Chang JS, Kondo, A. Synergistic enhancement of glycogen production in Arthrospira platensis by optimization of light intensity and nitrate supply. Bioresour. Technol.108: 211-215 (2012).

11.   Yoshie T, Nishiumi S, Izumi Y, Sakai A, Inoue J, Azuma T, Yoshida M. Regulation of the metabolite profile by an APC gene mutation in colorectal cancer. Cancer Sci.,103(6): 1010-21 (2012).

12.   Sakai A, Nishiumi S, Shiomi Y, Kobayashi T, Izumi Y, Kutsumi H, Hayakumo T, Azuma T, Yoshida M. Metabolomic analysis to discover candidate therapeutic agents against acute pancreatitis. Arch. Biochem. Biophys., 522(2): 107-120 (2012).

13.   Nishiumi S, Kobayashi T, Ikeda A, Yoshie T, Kibi M, Izumi Y, Okuno T, Hayashi N, Kawano S, Takenawa T, Azuma T, Yoshida M. A novel serum metabolomics-based diagnostic approach for colorectal cancer. PLoS ONE7(7): e40459 (2012).

14.   Lai P, Okazawa A, Izumi Y, Bamba T, Fukusaki E, Yoshikawa M, Kobayashi A. Gallic acid oxidizes Met-residues in peptides released from bovine β-lactoglobulin by in vitro digestion. J. Biosci. Bioeng.114(3): 297-305 (2012).

15.   Lai P, Okazawa A, Izumi Y, Bamba T, Fukusaki E, Yoshikawa M, Kobayashi A. Effect of gallic acid on peptides released by trypsin digestion of bovine a-casein. J. Biosci. Bioeng.115(3): 259-267 (2013).

16.   Takebayashi K, Hirose K, Izumi Y, Bamba T, Fukusaki E. Application of ion mobility-mass spectrometry to microRNA analysis. J. Biosci. Bioeng.115(3): 332-338 (2013).

17.   Kobayashi T, Nishiumi S, Ikeda A, Yoshie T, Sakai1 A, Matsubara A, Izumi Y, Tsumura H, Tsuda M, Nishisaki H, Hayashi N, Kawano S, Fujiwara Y, Minami H, Takenawa T, Azuma T, Yoshida M. A novel serum metabolomics-based diagnostic approach to pancreatic cancer. Cancer Epidem. Biomar. Prev.22(4): 571-579 (2013).

18.   Ohira H, Fujioka Y, Katagiri C, Mamoto R, Aoyama M, Izumi Y, Nishiumi S, Yoshida M, Usami M, Ikeda M. Butyrate attenuates inflammation and lipolysis generated by the interaction of adipocytes and macrophages.J. Atherosclero. Thromb.20(5): 425-442 (2013).

19.   Okada T, Fukuda S, Hase K, Nishiumi S, Izumi Y, Yoshida M, Hagiwara T, Kawashima R, Yamazaki M, Oshio T, Otsubo T, Inagaki-Ohara K, Kakimoto K, Higuchi K, Kawamura Y, Ohno H, Dohi T. Microbiota derived lactate accelerates colon epithelial cell turnover in starvation-refed mice. Nat. Commun.4: Article number 1654 (2013).

20.   Hasunuma T, Kikuyama F, Matsuda M, Aikawa S, Izumi Y, Kondo A. Dynamic metabolic profiling of cyanobacterial glycogen biosynthesis under conditions of nitrate depletion. J. Exp. Bot.64(10): 2943-2954 (2013).

21.   Izumi Y, Aikawa S, Matsuda F, Hasunuma T , Kondo A. Aqueous size-exclusion chromatographic method for the quantification of cyanobacterial native glycogen. J. Chrom. B930: 90-97 (2013).

22.   Aikawa S, Joseph A, Yamada R, Izumi Y, Yamagishi T, Matsuda F, Kawai H, Chang JS, Hasunuma T, Kondo A. Direct conversion of Spirulina to ethanol without pretreatment or enzymatic hydrolysis processes.Energy Environ. Sci.6: 1844-1849 (2013).

23.   Izumi Y, Aritake K, Urade Y, Fukusaki E. Practical evaluation of liquid chromatography/tandem mass spectrometry and enzyme immunoassay method for the accurate quantitative analysis of prostaglandins. J. Biosci. Bioeng.in press.

 

 

Book

1.         和泉自泰,福崎英一郎;シングルセル解析の最前線 (監修::神原秀紀,松永是,植田充美);第3 細胞内生体分子群の実測定量解析; 8. ナノLC/MSを用いた代謝物微量解析,194-200 (2010).

 

総説・解説

1.       河原秀久,和泉自泰,清水知香,小幡斉;醤油の研究と技術Aspergillus awamori No. 3由来複合酵素を用いた醤油粕からのグルコースの生産33(2): 95-99 (2007).

2.       河原秀久,和泉自泰,小幡斉;醤油の研究と技術Aspergillus awamori No.3由来複合酵素を用いた醤油粕からのエタノールの生産33: 275-280 (2007).

3.       蓮沼誠久藍川晋平, 和泉自泰近藤昭彦;微細藻類によるバイオリファイナリー生物工学会誌89(4): 181-183 (2011).

4.       Yoshida M, Hatano N, Nishiumi S, Irino Y, Izumi Y, Takenawa T, Azuma T. Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry. J. Gastroenterol.47: 9-20 (2012).

5.       吉田優,寺島禎彦,西海信,和泉自泰,東健,ガスクロマトグラフ質量分析計を用いたメタボローム解析による消化管疾患診断に向けて,分子消化器病,9(2), 22-27 (2012).

6.       平川あずさ,渡邊昌,和泉自泰,西海信,吉田優,五明紀春,玄米VS胚芽米,アンチ・エイジング医学,8(4) 586-591 (2012).

 

【受賞】

平成21年度 生物工学若手研究者の集い生物工学会特別賞

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